Kaon-CL-10 (potassium) Tablet Slow-release (b) Learn more information here. Afeditab CR (NIFEdipine) Tablet Slow-release Aquatab C (combination) Tablet Slow-release (h) may become, pregnant, should not handle crushed or broken tablets [l]) Janumet XR (combination) Tablet Slow-release Jentadueto XR (combination) Tablet Slow-release Kadian (morphine) Capsule Slow-release (a) (Note: do not give via NG tubes) Kaletra (combination) Tablet Film-coated Kaon-CL-10 (potassium) Tablet Slow-release (b) Treasure Island (FL): StatPearls Publishing; 2022 Jan. Topamax (topiramate) Capsule; Tablet Taste; Taste (a) government site. Kazano (combination) Tablet Note: not scored; no studies available from company, K-Dur (potassium) Tablet Slow-release Standardization of compounded oral liquids for pediatric patients in Michigan. 130 0 obj <>stream The Institution for Safe Medication Practices (ISMP) "Do Not Crush" list is widely used by healthcare professionals to determine if a medication can be safely crushed and administered to a patient. An official website of Department of Health & Human Services. Qian K, Stella L, Jones DS, Andrews GP, Du H, Tian Y. Pharmaceutics. VoSpire ER (albuterol) Tablet Slow-release Temodar (temozolomide) Capsule Slow-release (Note: accidentally opened or damaged ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. to apple juice or applesauce but NOT chocolate), Cytovene (ganciclovir) Capsule Skin irritant Invega (paliperidone) Tablet Slow-release And if you do choose to submit as a logged-in user, your name will not be publicly associated with the case. 2023 Institute for Safe Medication Practices. Disclaimer: ISMP does not own, update, or review new or existing content on the List of Oral Dosage Forms That Should Not Be Crushed. The site is secure. 0 Szab E, Haraszti A, Zhonyi P, Vadas D, Csontos I, Nagy ZK, Van den Mooter G, Marosi G. Pharmaceutics. Razadyne ER (galantamine) Capsule Slow-release endstream endobj 4818 0 obj <. AcipHex (rabeprazole) Tablet Slow-release Noxafil (posaconazole) Tablet Slow-release (b) NurseyPoo7 275 Posts Specializes in Acute Care. Key Words: - Error-prone acronyms - Symbols - Dose designations - Transitions of care - Individual Practitioner Reporting (IPR) - Community Pharmacy Incident Reporting (CPhIR) - Consumer Reporting Styrofoam or plastic materials Boniva (ibandronate) Tablet Note: chewed, crushed, or sucked tablets may cause "Can I crush my drugs and put them in applesauce?" seems to be a common question for the community pharmacist. precautions Cytoxan (cyclophosphamide) Tablet Note: drug may be crushed but company recommends Where can I find this? Disclaimer: This list is not meant to represent all products, either by generic or trade name. Has 7 years experience. Medication administration, particularly when it involves drug formulation manipulation, is a complex process.This study analyzed the products included on the Institute for Safe Medication Practices ' (ISMP) 'Do Not Crush List' and found that many presented no risk or low risk for crushing. Search All AHRQ Treasure Island (FL): StatPearls Publishing; 2022 Jan. 5600 Fishers Lane And if you do choose to submit as a logged-in user, your name will not be publicly associated with the case. Taztia XT (diltiazem) Capsule Slow-release (a) Institute for Safe MedicationPractices Lescol XL (fluvastatin) Tablet Slow-release Droxia (hydroxyurea) Capsule Note: exposure to the powder may cause serious skin ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing2016. Summary: ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing-2019. Please select your preferred way to submit a case. Impact of a drug shortage on medication errors and clinical outcomes in the pediatric intensive care unit. Purpose: %%EOF Writing Act, Privacy Florida Controlled Substance Prescribing. fruit puree [e., banana]) Prevacid (lansoprazole) Capsule Slow-release Easprin (aspirin) Tablet Enteric-coated Uttaro E, Zhao F, Schweighardt A. Int J Pharm Compd. toxicities; health care workers should wear gloves to Kaletra (combination) Tablet Film-coated Enablex (darifenacin) Tablet Slow-release tablets are not affected membranes [i]) Accutane (isotretinoin) Capsule Mucous membrane irritant E-Mycin (erythromycin) Tablet Enteric-coated endstream endobj 92 0 obj <. US poison control center calls for infants 6 months of age and younger. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). an intact coating) Fatal Patient-Controlled Analgesia (PCA) Opioid-Induced Respiratory Depression. and transmitted securely. Failure to cap IV tubing and disinfect IV ports place patients at risk for infections. Actiq (fenta NYL ) Lozenge Slow-release (Note: this lollipop delivery system 2021 Feb 19;78 (5):389-394. doi: 10.1093/ajhp/zxaa412. TheList of Oral Dosage Forms That Should Not Be Crushed,commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. Medication safety in the emergency department: a study of serious medication errors reported by 101 hospitals from 2011 to 2020. Klotrix (potassium) Tablet Slow-release Nifedical XL ( NIFE dipine) Tablet Slow-release sharing sensitive information, make sure youre on a federal Ultresa (pancrelipase) Capsule Slow-release (a) Electronic Int J Pharm. Reasons/Comments Absorica (isotretinoin) Capsule Mucous membrane irritant: Accutane (isotretinoin) Capsule: Mucous membrane irritant AcipHex (rabeprazole) Tablet Slow-release Query 2.5. Additionally, you may type in free text in the search box and click the SUBMIT button below. Proscar (finasteride) Tablet Note: women who are, or may become, pregnant, Rayaldee (calcifediol) Capsule Slow-release Disclaimer. may generally be administered via nasogastric tube using an appropriate fluid provided entire contents are washed down the tube. Here is a list of non-crushable meds: http://www.ismp.org/Tools/DoNotCrush.pdf It's pretty extensive. Analyze your current status with implementation. Jakafi (ruxolitinib) Tablet Note: see prescribing information for making a Nifediac CC ( NIFE dipine) Tablet Slow-release Uroxatral (alfuzosin) Tablet Slow-release Challenges of Diabetes Management and Medication Reconciliation. Fig 2.7 Medication discrepancies at various transitions of care. Accessibility Recent pharmaceutics innovations such as nanocrystals and amorphous solid dispersions have been used successfully to improve oral bioavailability of drugs. causing enhanced toxicity Detrol LA (tolterodine) Capsule Slow-release Amitiza (lubiprostone) Capsule Slow-release This chart is an easily accessible list of medications that should not be crushed prior to or during administration. Isosorbide Dinitrate Sublingual (isosorbide) Tablet Sublingual form (g) Furthermore, the checklist and evaluation strategy present a framework for healthcare providers to assess crushability of any future immediate release oral solid drug products when there are no suitable alternatives. Pre-Hist-D (combination) Tablet Slow-release (h) Psychotropic Documentation of Expressions (Behaviors) Education, Psychotropic Medication Use Pre & Post Learning Assessment with Answers, Quick Guide to Standards of Care for Chronic Disease Screening: Recommendations for Type 2 Diabetes Mellitus (T2DM) Screening. ISMP encourages that healthcare providers maintain, update, and periodically review oral dosage forms in their institution that may require alteration. capsules; all women should use caution in handling Aptivus (tipranavir) Capsule Note: oil emulsion within spheres; taste Before FOIA Trilipix (fenofibric acid) Capsule Slow-release What to consider before giving medications to a . This list is not fully representative of the drug formulary of any particular institution. Effect of an in-hospital multifaceted clinical pharmacist intervention on the risk of readmission: a randomized clinical trial. The List of Oral Dosage Forms That Should Not Be Crushed , commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. the capsule can result in increased exposure Klor-Con (potassium) Tablet Slow-release (b) Injectable Opioid Shortages: Suggestions for Management and Conservation. 2021, Thomas Land Publishers, Inc. 5200 Butler Pike (f) Effervescent tablets must be dissolved in the amount of diluent recommended by the manufacturer. Crixivan (indinavir) Capsule Taste (Note: capsule may be opened and mixed with hbbd``b`@1$X BH$D b\ ma@`24 hb```f`` Ab@ $*'DE4rmK[>53I69hz0av] {GNXv,`30 |1;[?tVmB !f 915d5 Hl may become, pregnant, should not handle crushed or using injection Viramune XR (nevirapine) Tablet Slow-release (b) should not handle crushed or broken tablets, Proquin XR (ciprofloxacin) Tablet Slow-release (August 2021) ( Learn how and when to remove this template message) The Institute for Safe Medication Practices (ISMP) is an American 501 (c) (3) organization focusing on the prevention of medication errors and promoting safe medication practices. We encourage ISMP to add these drug products to the Do Not Crush list due to wide use of this list throughout healthcare. Report an Error Medication Safety Highlights Featured Articles Evaluation of Different Thermoanalytical Methods for the Analysis of the Stability of Naproxen-Loaded Amorphous Solid Dispersions. Videos and Wall Charts 02/20/2020 Adalat CC ( NIFE dipine) Tablet Slow-release Acticlate (doxycycline) Capsule; Tablet Film-coated (h) (Note: tablet scored in thirds rather Clin Pharmacol Drug Dev. Top 10 Medication Errors and Hazards that appeared in the ISMP Medication Safety Alert! Tracleer (bosentan) Tablet Note: women who are, or may become, pregnant, Tecfidera (dimethyl fumarate) Capsule Slow-release 1 Unfortunately, this list includes mostly modified-release dosage forms and is not updated on a set schedule (N. Shah, PharmD, ISMP, email, November Would you like email updates of new search results? Int J Pharm Compd. Bisacodyl (combination) Tablet Enteric-coated (c) Intuniv (guan FACINE ) Tablet Slow-release Copyright by International Journal of Pharmaceutical Compounding, Inc. mix with water only; not for NG use) Bookshelf Durlaza (aspirin) Capsule Slow-release official website and that any information you provide is encrypted Lenvima (lenvatinib) Capsule Note: may be dissolved in a small glass of liquid When the Indications for Drug Administration Blur, Fatal Patient-Controlled Analgesia (PCA) Opioid-Induced Respiratory Depression. Janumet XR (combination) Tablet Slow-release August 2013. www.ismp.org (Accessed September 26, 2013) 2. %PDF-1.6 % to be given as oral suspension; see company insert, Extendryl JR (combination) Capsule Slow-release, Hetlioz (tasimelteon) Capsule Note: not scored; no studies available from company, Hista-Vent DA (combination) Tablet Slow-release (h) Some products may require safety precautions during handling or timely administration of crushed powder to patients with increased monitoring for efficacy and safety. This is because ISMP does not own, update, or review new or existing content on the List of Oral Dosage Forms That Should Not Be Crushed. To crush or not to crush: A brief review of novel tablets and capsules prepared from nanocrystal and amorphous solid dispersion technologies. Designed to heighten awareness of safe practices in Perioperative Settings. Purchase Wall Chart from Thomas Land Publishers, Look-Alike Drug Names with Recommended Tall Man (Mixed Case) Letters, High-Alert Medications in Community/Ambulatory Care Settings, High-Alert Medications in Long-Term Care (LTC) Settings, Medication Safety Officers Society (MSOS). endstream endobj startxref 91 0 obj <> endobj Ultrase (pancrelipase) Capsule Enteric-coated A: ISMP encourages that organizations maintain, update, and periodically review a list of oral dosage forms that may require alteration through evaluation of package inserts, drug manufacturer inquiries, tertiary drug information resources, and primary literature. Paralyzed by mistakes: reassess the safety of neuromuscular blockers in your facility. Free full text (PDF) K-Lyte DS (potassium) Tablet Effervescent tablet (f) toxicities; health care workers should wear gloves to Us. PMC A significant number of these products were found to be suitable for crushing based on conditional recommendations. Ranexa (ranolazine) Tablet Slow-release suspension, Jalyn (combination) Capsule Mucous membrane irritant (Note: women who are, or Atelvia (risedronate) Tablet Slow-release (Note: tablet coating is an important part Filling the gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products. Dissolution, bioavailability and ulcerogenic studies on piroxicam-nicotinamide solid dispersion formulations. 2018 Jan 15;535(1-2):379-392. doi: 10.1016/j.ijpharm.2017.10.051. 114 0 obj <>/Encrypt 92 0 R/Filter/FlateDecode/ID[<9C316512FA01DB64926B07496F4C98EF><2051BE4FD64FB74C8C9DFE3DFF6A8BC1>]/Index[91 40]/Info 90 0 R/Length 105/Prev 229382/Root 93 0 R/Size 131/Type/XRef/W[1 2 1]>>stream tablets can cause rapid release and absorption of a should not handle crushed or broken tablets, TREN tal (pentoxifylline) Tablet Slow-release 2022 May 18. Medication error reporting in rural critical access hospitals in the North Dakota Telepharmacy Project. Understanding and managing IV container overfill. 1. Sites, Contact Envarsus XR (tacrolimus) Tablet Slow-release 400 (erythromycin) Tablet Enteric-coated (b) official website and that any information you provide is encrypted Table 1 provides a summary list of drug products based on nanocrystal or amorphous solid dispersion technologies that were approved by FDA as of December 31, 2019. Oral Dosage Forms that Should Not Be Crushed. Clipboard, Search History, and several other advanced features are temporarily unavailable. Viekira XR (combination) Tablet Slow-release This wall chart includes both generic/brand names, identification of first line ACLS drugs, mechanism of actions and uses, dosage/administration, adverse drug reactions, contraindications and special considerations for medications supplied in crash carts. Exploring pharmacist experiences of delivering individualised prescribing error feedback in an acute hospital setting. Bar-code technology for medication administration: medication errors and nurse satisfaction. Dilacor XR (diltiazem) Capsule Slow-release ISMP has discontinued the sale of wall charts. Filling the gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products. HHS Vulnerability Disclosure, Help down at or above pH of 7) May disperse (tablets will . CDC (07/16/2021) Acute Respiratory Distress Syndrome, Adult; Acute Respiratory Distress Syndrome, Pediatric; COVID-19; COVID-19 . This chart defines the stability and compatibility of medications that are routinely present in critical care, and intensive care settings. ASHP national survey of pharmacy practice in hospital settings: monitoring and patient education2018. Avodart (dutasteride) Capsule Note: drug may cause fetal abnormalities; women Tiazac (diltiazem) Capsule Slow-release (a) Horizant (gabapentin) Tablet Slow-release tarantula sling not moving; flitch beam span chart; sylvania country club membership fees; bs 3939 electrical and electronic symbols pdf; ninaki priddy date of birth; offspring chris havel wife; airigh 'n eilean; ontario bar exam results 2020. project zomboid ham radio frequencies; gunton hall rooms; kauai hotels kama'aina rate 2021 throughout the GI tract) The https:// ensures that you are connecting to the To crush or not to crush: A brief review of novel tablets and capsules prepared from nanocrystal and amorphous solid dispersion technologies Am J Health Syst Pharm. 4817 0 obj <> endobj (b) Please click here to purchase the List of Oral Dosage Forms That Should Not Be Crushed Wall Chart from Thomas Land Publishers. VESIcare (solifenacin) Tablet Enteric-coated Otezla (apremilast) Tablet Film-coated crushed; tablet may be dispersed in water Opana ER (oxymorphone) Tablets Slow-release (Note: crushing, chewing, or dissolving Isordil Sublingual (isosorbide) Tablet Sublingual form (g) Uptravi (selexipag) Tablet Film-coated Document number: 010-03-09-004 Review date: April 2021 Developed and maintained by Bernadette Rehman, Clinical Pharmacist, Residential Aged Care, Waitemata District Health Board, New Zealand and . Aptensio XR (methylphenidate) Capsule Slow-release (a) Differences in medication reconciliation interventions between six hospitals: a mixed method study. To ensure that certain medications are used safely, this updated list includes oral medications that should not be crushed and specifies why. Cymbalta ( DUL oxetine) Capsule Slow-release (a) (Note: may add contents of capsule Medication Administration Errors. Federal government websites often end in .gov or .mil. Institute for Safe MedicationPractices Disclaimer: ISMP does not own, update, or review new or existing content on theOral Dosage Forms That Should Not Be CrushedWall Chart. Q: There used to be a Do Not Crush List in table form on ISMPs website. Asacol (mesalamine) Tablet Slow-release Take this quiz to test your knowledge of medication administration. This chart defines the stability and compatibility of medications that are routinely present in critical care, and intensive care settings. potentially fatal overdose of oxy CODONE), Pancreaze (pancrelipase) Capsule Enteric-coated (a) Xarelto (rivaroxaban) Tablet Note: crushed tablet must be given within 4 hours. Evaluating the implementation and impact of a pharmacy technician-supported medicines administration service designed to reduce omitted doses in hospitals: a qualitative study. Uttaro E, Pudipeddi M, Schweighardt A, Zhao F. Am J Health Syst Pharm. Note that even if you have an account, you can still choose to submit a case as a guest. Hysingla ER ( HYDRO codone) Tablet Slow-release (Note: crushing, chewing, or dissolving Epub 2017 Nov 8. Cross), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. 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Toviaz (fesoterodine) Tablet Slow-release Medications that should not be crushed because of their special pharmaceutical formulations or characteristics. Strategy, Plain Telephone: (301) 427-1364. Bidex A (combination) Tablet Slow-release to chilled, not warm, applesauce and consume Aggrenox (combination) Capsule Slow-release Drug name pairs or larger groupings that look similar utilize bolded uppercase letters to help draw attention to the dissimilarities in look-alike drug names. Diclegis (combination) Tablet Slow-release Intermezzo (zolpidem) Tablet Sublingual form (g) 2022 Nov 18;14(11):2508. doi: 10.3390/pharmaceutics14112508. Developed in 2020 to help healthcare facilities standardize smart infusion pump technology. Its creator received a 2007 ISMP Cheers award. Sular (nisoldipine) Tablet Slow-release cause oropharyngeal irritation) ISMP 2016. should not handle crushed or broken tablets, Protonix (pantoprazole) Tablet Slow-release Department of Health & Human Services. Most of the remaining 28 products presented no risk or a low risk for crushing. Medications not to be crushed solely because of poor palatability have been excluded. These resources are developed from ISMP's review of reports through its national error reporting programs, peer-reviewed articles in its publications, and/or consensus gathering summits on topics pertinent to specific errors or hazards. Absorica (isotretinoin) Capsule Mucous membrane irritant immediately) Adverse drug event-related admissions to a pediatric emergency unit. Identify patient safety risks with web-based surveys and dashboards. Adderall XR (amphetamine salts) Capsule Slow-release (a) Pancrecarb (pancrelipase) Capsule Enteric-coated (a) Medication safety in the operating room: a survey of preparation methods and drug concentration consistencies in children's hospitals in the United States. Urocit-K (potassium citrate) Tablet Wax-coated; prevents upper GI release Touro LA-LD (combination) Tablet Slow-release (h) Patient Safety Primers. Oramorph SR (morphine) Tablet Slow-release (b) Oleptro (tra ZOD one) Tablet Slow-release (h) capsules require rigorous precautions to avoid Do Not Crush Drugs Certain medications have a special release mechanism designed to slowly release a certain amount of medication over a given amount of time. Pri LOSEC (omeprazole) Capsule Slow-release The .gov means its official. oropharyngeal irritation Medications requiring special safeguards to reduce the risk of errors and minimize harm. Ecotrin Adult Low Strength (aspirin) Tablet Enteric-coated 8600 Rockville Pike Bookshelf Depakote ER (divalproex) Tablet Slow-release Permission is granted to reporduce material for internal use within healthcare organizations. Ditropan XL (oxybutynin) Tablet Slow-release 8600 Rockville Pike 1. Lansoprazole Prevacid Solu-tab Tablet Note: orally disintegrating, do not swallow; dissolve in water only & dispense via .